A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/36 (2006.01)
Patent
CA 2653551
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.
L'invention concerne un procédé amélioré permettant de produire une ossature de matrice acellulaire naturelle destinée à être utilisée par la suite comme tissu de remplacement artificiel, par exemple pour la vessie. La décellularisation se fait sur une vessie expansée ou distendue et le produit conserve la solidité et la compliance du matériau naturel. L'invention concerne également l'utilisation de ces ossatures de matrices comme matériau de cicatrisation ainsi que pour étudier la structure et la fonction tissulaire in vitro.
Bolland Fiona
Ingham Elleen
Korossis Sotirios
Southgate Jennifer
Ridout & Maybee Llp
Tissue Regenix Limited
University Of Leeds
University Of York
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