Improvements relating to pharmaceutical compositions

A - Human Necessities – 61 – K

Patent

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A61K 9/16 (2006.01)

Patent

CA 2735698

The present invention provides a substantially solvent-free nano-dispersion of an active in a carrier, wherein the carrier comprises an enteric carrier soluble at intestinal pH, but insoluble at stomach pH, and wherein the enteric carrier comprises at least 50% by weight of the nano-dispersion; and processes for the preparation of a substantially solvent-free nano-dispersion of an active in a carrier.

La présente invention concerne une nano-dispersion sensiblement dépourvue de solvant dun principe actif dans un véhicule, le véhicule comprenant un véhicule gastrorésistant soluble à pH intestinal, mais insoluble à pH gastrique, et le véhicule gastrorésistant comprenant au moins 50 % en poids de la nano-dispersion; ainsi que des procédés de préparation dune nano-dispersion sensiblement dépourvue de solvant dun principe actif dans un véhicule.

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