Improving glucose tolerance

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/135 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2182620

A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example <u>N</u>,<u>N</u>- dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride optionally in the form of its monohydrate) is used for improving the glucose tolerance of humans having impaired glucose tolerance or non-insulin dependent diabetes mellitus.

Composé répondant à la formule (I), ou son sel pharmaceutiquement acceptable. Dans ladite formule (I), R¿1? et R¿2?, indépendamment l'un de l'autre, représentent H ou méthyle (par exemple l'hydrochlorure de <u>N</u>,<u>N</u>-diméthyl-1-[1-(4-chlorophényl)cyclobutyl]-3-méthylbutylamine, éventuellement sous la forme de son sel). Ledit composé sert à améliorer la tolérance au glucose des personnes atteintes d'intolérance au glucose ou de diabète sucré non insulino-dépendant.

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