In-situ hybridization to detect rna and dna markers

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2695369

The present invention provides probes, kits and methods for specif-ically binding mRNA of target cells, e.g., fetal cells, that allows visualization of the target cells, under conditions that allows a second probe to specifically bind the target cell's chromosomal DNA.

La présente invention concerne des sondes, des trousses et des procédés permettant une liaison spécifique avec ARNm de cellules cibles, notamment de cellules ftales. L'invention concerne la visualisation des cellules cibles dans des conditions autorisant une seconde sonde à se lier spécifiquement avec l'ADN chromosomique des cellules cibles.

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