In situ synthesis of radiopharmaceuticals

C - Chemistry – Metallurgy – 07 – F

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C07F 13/00 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07F 1/08 (2006.01) C07F 3/06 (2006.01) C07F 5/00 (2006.01) C07F 11/00 (2006.01) C07F 15/00 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2101642

2101642 9214492 PCTABS00015 The present invention relates to a process of making radiopharmaceuticals in situ, i.e. wherein a radionuclide and an acyclic ligand react with constituents of the complex forming reaction solution to produce an administratable radiopharmaceutical agent. By forming radiopharmarceuticals according to the present invention, it is possible to obtain radiopharmaceuticals previously unattainable because of problems associated with the ligand synthesis or with the complex forming reaction.

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