In vitro antibody affinity maturation using alanine scanning...

Details In vitro antibody affinity maturation using alanine scanning... In vitro antibody affinity maturation using alanine scanning...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/10 (2006.01) C07K 16/46 (2006.01) C12Q 1/68 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183550

A method of mutagenizing antibodies to produce modified antibodies, modified antibodies, DNA encoding the modified antibodies as well as diagnostic kits and pharmaceutical compositions comprising the antibodies or DNA the provided.

L'invention porte sur un procédé de mutagénèse d'anticorps dans le but de produire des anticorps modifiés, sur des anticorps modifiés, sur de l'ADN codant les anticorps modifiés, ainsi que sur du matériel de diagnostic et des compositions pharmaceutiques comprenant les anticorps ou l'ADN susmentionnés.

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