G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01)
Patent
CA 2284790
Especially nodal conditions and tumour size, histological type, degree of differentiation and receptor condition are used nowadays for the prognosis and further planning of patients with carcinoma of the breast. Emphasis is placed on evaluation of the condition of the axillary lymph node. Patients with a negative axillary lymph node condition generally receive no after-treatment, as their prognosis is better; yet 30 % of these patients suffer relapses. The method proposed by this invention should make it possible to determine the patient's risk of recividation. In accordance with the invention, the invention makes it possible to predict the further evolution of patients with carcinoma of the breast by means of a qualitative or quantitative determinatin of T1 protein and/or T1-mRNA is sample material taken from the patients.
On se sert actuellement pour le pronostic et la planification thérapeutique ultérieure de patientes atteintes d'un carcinome mammaire en premier lieu du bilan relatif aux noeuds ainsi que de la taille de la tumeur, du type histologique, du degré de différenciation et du bilan des récepteurs, l'accent étant mis sur l'évaluation du bilan des noeuds lymphatiques axillaires. Les patientes sans noeuds lymphatiques axillaires ne suivent généralement pas de traitement postérieur, car le pronostic est meilleur; il y a pourtant récidive pour 30 % de ces patientes. Le procédé selon l'invention doit permettre de déterminer les patientes risquant une récidive en prévoyant l'évolution pathologique future des patientes atteintes d'un carcinome mammaire par la détermination qualitative ou quantitative de protéine T1 et/ou T1-mRNA dans des échantillons prélevés sur les malades.
Goudreau Gage Dubuc
Gsf - Forschungszentrum Fur Umwelt Und Gesundheit Gmbh
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