In vitro peptide or protein expression library

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/10 (2006.01) C07K 14/01 (2006.01) C07K 14/02 (2006.01) C12N 15/11 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C40B 50/06 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2282497

The present invention provides a method of producing an in vitro peptide or protein expression library which displays a diverse population of peptides or proteins, wherein the peptides or proteins are specifically associated with the DNA encoding them through covalent protein:DNA binding expecially through the use of cis-acting proteins, the library itself, DNA molecules encoding the library and uses of the expression library.

La présente invention concerne un procédé de production d'une bibliothèque d'expression in vitro de protéine ou d'un peptide présentant une population diverse de peptides ou de protéines dans laquelle lesdits peptides ou protéines sont spécifiquement associés à l'ADN qui les code par le biais d'une protéine covalente: L'invention concerne également un ADN liant spécialement par le biais de protéines à activité cis, ladite bibliothèque, des molécules d'ADN codant ladite bibliothèque et des utilisations de ladite bibliothèque d'expression.

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