In vitro screening method for identifying selective binding...

Details In vitro screening method for identifying selective binding... In vitro screening method for identifying selective binding...

G - Physics

01

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G01N 33/566 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/4045 (2006.01) A61K 31/48 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 45/00 (2006.01) A61P 25/06 (2006.01) C12Q 1/02 (2006.01) C12Q 1/34 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2359360

The invention relates to selective binding partners for 5-HT5-receptors, methods, in particular screening methods, for identifying and characterizing such binding partners, as well as pharmaceutical compositions containing said binding partners and their use in the treatment of cerebrovascular diseases such as migraine.

L'invention concerne des partenaires de liaison sélectifs pour les récepteurs 5-HT5, ainsi que des procédés d'identification et de caractérisation de tels partenaires de liaison, notamment des procédés de criblage. Elle concerne également des compositions pharmaceutiques contenant ces partenaires de liaison, et leur utilisation pour le traitement d'affections cérébrovasculaires, telles que la migraine.

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