In vitro test for dermal corrosive properties

Details In vitro test for dermal corrosive properties In vitro test for dermal corrosive properties

G - Physics

01

N

G01N 33/48 (2006.01) A61K 49/00 (2006.01) G01N 31/22 (2006.01) G01N 33/15 (2006.01) G01N 33/483 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2140879

An in vitro test kit and an in vitro test method which determine dermal corrosion properties of a test substance and/or mix- ture are disclosed. The test substance is applied directly to a biobarrier designed to give corrosion times comparable to those of the in vivo dermal corrosion test. A corrosive test substance destroys and passes through the biobarrier, after which the test sub- stance enters and reacts with the adjacent chemical detection system, where the test substance is detected. The detection time, or the time from application to detection, can be correlated with UN Packing Groups and EEC classes.

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