In vivo addition of telomeric repeats to exogenous dna...

Details In vivo addition of telomeric repeats to exogenous dna... In vivo addition of telomeric repeats to exogenous dna...

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12N 9/12 (2006.01) C12N 15/80 (2006.01)

Patent

CA 2336132

This invention relates to compositions and methods useful for producing extrachromosomal DNA. More specifically, the present invention relates to compositions and methods for producing extrachromosomal DNA based on the unexpected discovery that the Pestalotiopsis fungi add one or more telomeric repeats to the ends of exogenous DNA.

L'invention concerne des compositions et des procédés utiles pour la constitution d'ADN extrachromosomique. Plus précisément, l'invention concerne des compositions et des procédés qui permettent de constituer de l'ADN extrachromosomique en utilisant la découverte inattendue selon laquelle les champignons Pestalotiopsis ajoutent une ou plusieurs répétitions télomériques aux extrémités de l'ADN exogène.

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