In vivo brain elasticity measurement by magnetic resonance...

A - Human Necessities – 61 – B

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A61B 5/055 (2006.01)

Patent

CA 2520566

A vibrator coil (10) is applied to the skull (30) by adaptation of a commercially available transcranial Doppler monitoring harness (40) during MR applies mechanical waves in the acoustic waves through the skull to the brain. Utilizing magnetic resonance elastography (MRE), non-invasive estimation of tissue elastic properties in three dimensions occurs. The propagation of the acoustic waves through brain tissue, coupled to phase alteration of voxel isochromats in the presence of applies motion encoding magnetic field gradients allows measurements of brain elasticity.

L'invention concerne une bobine vibratoire (10) appliquée sur un crâne (30) par l'adaptation d'un harnais (40) de surveillance Doppler transcrânien disponible dans le commerce, lors de l'application de RM, appliquant des ondes mécaniques dans des ondes acoustiques traversant le crâne jusqu'au cerveau. L'utilisation de l'élastrographie par résonance magnétique (ERM) permet une estimation non invasive des propriétés élastiques tissulaires, en trois dimensions. La propagation des ondes acoustiques à travers le tissu cérébral, conjointement à l'altération de phase d'isochromates de voxel en présence d'un mouvement appliqué codant des gradients de champ magnétique permet d'obtenir des mesures de l'élasticité cérébrale.

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