In vivo detection of apoptosis

Details In vivo detection of apoptosis In vivo detection of apoptosis

G - Physics

01

N

G01N 33/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2626392

The invention provides methods and products, such as kits, useful for determining the apoptotic state of cells in an organism, comprising detecting the presence or abundance of at least one caspase affinity labeling agent in the cells of an animal into which at least one caspase affinity labeling agent has been introduced, wherein the presence or abundance of the caspase affinity labeling agent correlates with the apoptotic state of the cells.

L'invention concerne des méthodes et des produits, tels que des trousses, utiles pour déterminer l'état apoptotique de cellules dans un organisme. Les méthodes consistent à détecter la présence ou l'abondance d'au moins un agent de marquage d'affinité pour les caspases dans les cellules d'un animal dans lequel au moins un agent de marquage d'affinité pour les caspases a été introduit, la présence ou l'abondance de l'agent de marquage d'affinité pour les caspases étant corrélée avec l'état apoptotique des cellules.

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