In-vivo diagnostic process by near infrared radiation

C - Chemistry – Metallurgy – 09 – B

Patent

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C09B 23/01 (2006.01) A61K 49/00 (2006.01) C09B 23/08 (2006.01) C09B 69/10 (2006.01)

Patent

CA 2205906

A novel use is provided herein for certain novel compounds for an in vivo diagnostic method based on near infrared radiation. The novel compounds are water-soluble dyes and their biomolecule adducts. Each such dye or adduct has specific photophysical and pharmaco-chemical properties, which make them suitable as a contrast medium for fluorescence and transillumination diagnostics in the NIR range.

Selon un procédé de diagnostic in vivo, par rayons infrarouges proches (rayons I.R. proches), on utilise des colorants solubles dans l'eau et leurs produits d'addition biomoléculaires ayant des propriétés photophysiques et pharmacochimiques déterminées comme agents contrastants le diagnostic par fluorescence et par transillumination dans le domaine spectral des rayons infrarouges proches. L'invention concerne également de nouveaux colorants et des agents pharmaceutiques contenant ces colorants.

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