In vivo efficacy of ny-eso-1 plus adjuvant

Details In vivo efficacy of ny-eso-1 plus adjuvant In vivo efficacy of ny-eso-1 plus adjuvant

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2540764

The invention relates to the discovery that administration of NY-ESO-1 protein, in combination with a saponin based adjuvant leads to an unexpectedly strong immune response against NY-ESO-1 expressing cells. Preferably, the combination is administered intramuscularly.

La présente invention concerne la découverte du fait que l'administration d'une protéine NY-ESO-1, combinée à un adjuvant à base de saponine, conduit à une réponse immunitaire étonnamment forte contre des cellules exprimant NY-ESO-1. Cette combinaison est de préférence administrée par voie intramusculaire.

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