A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/04 (2006.01) G01T 1/161 (2006.01) G01T 1/164 (2006.01)
Patent
CA 2706017
Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18F, 123I, 124I, 125I, or 11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.
L'invention concerne des traceurs radiomarqués de sulfotransférases (SULT), leur synthèse et leur utilisation. L'invention concerne des phénols, naphtols, coumarines et flavones substitués radiomarqués avec 18F, 123I, 124I, 125I ou 11C. L'invention concerne également des techniques in vivo permettant d'utiliser ces traceurs et d'autres traceurs en tant qu'outils analytiques et de diagnostic pour étudier une distribution et une activité de sulfotransférases, chez des êtres sains et malades, et pour évaluer des interventions thérapeutiques.
Barrio Jorge R.
Kepe Vladimir
Satyamurthy Nagichettiar
Small Gary W.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Regents Of The University Of California
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