A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/045 (2006.01) A61K 31/22 (2006.01) A61K 38/18 (2006.01)
Patent
CA 2000940
ABSTRACT IN VIVO NEUROTROPHIC CYTOPROTECTIVE ALCOHOLS A method for treating or preventing neuronal injury in a mammal, comprising the step of administering in vivo a therapeutically effective amount of a long-chain fatty alcohol having from about 23 to about 29 carbon atoms or prodrug esters thereof. Also disclosed are pharmacological compositions containing from 0.01 mg/kg to about 20 mg/kg of the fatty alcohol. The method and compositions are useful in: treating traumatic injury, chemical injury and injury due to disease; promoting and accelerating recovery of behavioral function after such injury; preventing neuronal injury or death; improving training and memory functions; and protecting neurons against injury. DJP-5564.pct:djp4/nai6 BORGJ.01C 101089
Borg Jacques
Cotman Carl W.
Kesslak J. Patrick
Borg Jacques
Cotman Carl W.
Kesslak J. Patrick
Swabey Ogilvy Renault
The Regents Of The University Of California
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