In vivo nucleic acid hybridization method

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2167804

A method of nucleic acid hybridization in living cells is described, which is useful for detecting, quantitating and locating a specific nucleic acid in a cell or tissue, for selecting cells based on the expression or presence of a specific nucleic acid, and for monitoring the amount and location of a specific nucleic acid over time or under various inducing or inhibiting conditions.

Procédé d'hybridation d'acide nucléique dans des cellules vivantes servant à détecter, quantifier et localiser un acide nucléique donné dans une cellule ou un tissu, à sélectionner des cellules en se basant sur l'expression ou la présence d'un acide nucléique donné, et à contrôler la quantité et la localisation d'un acide nucléique donné dans le temps ou sous l'effet de facteurs inducteurs ou inhibiteurs.

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