In vivo protein synthesis method

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/02 (2006.01) C07K 14/245 (2006.01) C07K 14/61 (2006.01) C07K 14/805 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 9/78 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2264550

A method of overproducing proteins which are initiated with an amino acid other than methionine, in which methionyl-tRNA transformylase and, optionally, the appropriate tRNA synthetase are overexpressed in a host cell.

Procédé d'hyperproduction de protéines qui sont initiées au moyen d'un acide aminé autre que la méthionine. Dans ledit procédé, de la méthionyl-ARNt transformylase et, éventuellement, l'ARNt synthétase appropriée sont surexprimées dans une cellule hôte.

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