C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/36 (2006.01) A01N 63/00 (2006.01) A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61K 39/39 (2006.01) A61P 31/04 (2006.01) C12N 1/20 (2006.01) C12N 1/38 (2006.01)
Patent
CA 2089552
This invention provides a bacterin comprising a virulent Mycoplasma hyopneumoniae isolate, inactivated with binary ethyleneimine, in an amount effective to immunize a swine against infection by Mycoplasma hyopneumoniae and a suitable phy- siologically acceptable carrier. The invention also provides a method of producing this bacterin. The invention further provides a method of inactivating a virulent strain of Mycoplasma hyopneumoniae by contacting the Mycoplasma hyopneumoniae with bi- nary ethyleneimine. Finally, the invention also provides a method of immunizing swine against infection by Mycoplasma hyop- neumoniae comprising administering to the swine a dose of the bacterin so as to immunize the swine.
Dayalu Krishnaswamy I.
Petersen Gary R.
Gowling Lafleur Henderson Llp
Solvay Animal Health Inc.
Wyeth Holdings Corporation
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