Inactivation of hiv co-receptors as therapy for hiv infection

C - Chemistry – Metallurgy – 12 – N

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C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2273192

The present invention provides compositions and methods for the treatment and/or prevention of HIV-1 infection. In particular, the present invention employs novel compositions and methods for preventing the cell surface expression of a co-receptor necessary for the binding of HIV to its target cells.

Cette invention a trait à des compositions ainsi qu'aux méthodes afférentes visant au traitement et/ou à la prévention de l'infection à virus de l'immunodéficience humaine (VIH). On fait notamment appel, dans le cadre de cette invention, à de nouvelles compositions afin d'empêcher l'expression cellulaire en surface d'un co-récepteur nécessaire à la fixation du virus VIH à ses cellules cibles et l'on applique, pour ce faire, les méthodes afférentes.

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