Inactivation of west nile virus and malaria using...

Details Inactivation of west nile virus and malaria using... Inactivation of west nile virus and malaria using...

A - Human Necessities

61

K

A61K 41/00 (2006.01) A61K 31/7056 (2006.01)

Patent

CA 2474448

Methods and apparatuses are provided for inactivation of parasites (Pl. falciparum) or virus (West Nile Virus) in fluids. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic amount of a photosensitizer (riboflavin) to a fluid and exposing the fluid to photoradiation sufficient to activate the photosensitizer whereby microorganisms are inactivated.

L'invention concerne des procédés et appareils pour inactiver des microorganismes dans des fluides ou sur des surfaces. De préférence, lesdits fluides contiennent du sang ou des produits sanguins et comprennent des protéines biologiquement actives. Des procédés préférés comprennent les étapes consistant à ajouter à un fluide une quantité efficace non toxique d'un photosensibilisant puis à exposer ledit fluide à un rayonnement lumineux suffisamment puissant pour activer le photosensibilisant et inactiver ainsi les microorganismes.

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