Incorporation of pyridoxal phosphate in dry analytical...

Details Incorporation of pyridoxal phosphate in dry analytical... Incorporation of pyridoxal phosphate in dry analytical...

C - Chemistry, Metallurgy

12

Q

150/9, 150/3.2

C12Q 1/00 (2006.01) C12Q 1/26 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 1182726

Abstract of the Disclosure Enzymes which are activated by pyridoxal phosphate are assayed in a dry analytical element which includes a high coverage of pyridoxal phos- phate. The coverage of pyridoxal phosphate is such that the multiplication product of the coverage and the spreading coefficient of the element results in a reagent mixture concentration of at least about 0.9 mmole per liter when a liquid sample is contacted with the element thereby eliminating the need for a preincubation of the sample with a solution contain- ing pyridoxal phosphate. The reactions for the determination of the enzymes are initiated by contact of the dry elements with a liquid sample.

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