Increased-dosage nelfinavir tablet and method of making same

Details Increased-dosage nelfinavir tablet and method of making same Increased-dosage nelfinavir tablet and method of making same

A - Human Necessities

61

K

A61K 31/472 (2006.01) A61J 3/06 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2398226

A high-dosage nelfinavir tablet having a nelfinavir binder weight ratio of from about 3:1 to about 5:1 is described. The high-dosage nelfinavir tablets are made in a process in which a granulated mixture of a nelfinavir compound and a binder is formed in a granulating process, and then processed to form the tablets. In the granulating process, moisture is added and mechanical energy is applied to the mixture, and the mixture is cured without addition of moisture or application of mechanical energy.

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