C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/12 (2006.01) C12P 5/02 (2006.01)
Patent
CA 2737158
The invention features methods for producing isoprene from cultured cells using a feedback- resistant mevalonate kinase polypeptide, such as an archaeal mevalonate kinase polypeptide from Methanosarcina mazei. The resulting isoprene compositions may have increased yields and/or purity of isoprene.
La présente invention concerne des procédés de production d'isoprène à partir de cellules cultivées au moyen d'un polypeptide mévalonate kinase résistant à la rétroaction, tel qu'un polypeptide mévalonate kinase de la période archéenne provenant de Methanosarcina mazei. Les compositions d'isoprène résultantes peuvent avoir des rendements et/ou une pureté d'isoprène augmentés.
Beck Zachary Q.
Calabria Anthony R.
Miller Michael C.
Nielsen Alex T.
Vaviline Dmitrii V.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Danisco Us Inc.
The Goodyear Tire & Rubber Company
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