Increased solubility flavanolignan preparations

Details Increased solubility flavanolignan preparations Increased solubility flavanolignan preparations

A - Human Necessities

61

K

A61K 31/79 (2006.01)

Patent

CA 2458963

The inventors have devised novel approaches for the preparation of flavanolignan compositions of enhanced solubility and substantially free of toxic contaminants. Such novel approaches are based on spray drying or lyophilizing to dry a diluted preparation of flavanolignan. These approaches avoid the use of toxic excipients and or carriers commonly used to precipitate flavanolignan concentrates and thus address the drawbacks of existing methods and compositions.

L'invention se rapporte à de nouveaux procédés de préparation de compositions de flavonolignans à solubilité améliorée et sensiblement dépourvus de contaminants toxiques. Selon les nouveaux procédés de l'invention, on déshydrate une préparation diluée de flavonolignan par atomisation ou lyophilisation. Les procédés précités permettent, en évitant l'utilisation d'excipients toxiques et/ou des véhicules habituellement utilisés pour précipiter les concentrés de flavonolignan, de remédier aux inconvénients présentés par les procédés et compositions existants.

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