Increasing atp availability by inhibition of creatine kinase...

A - Human Necessities – 61 – K

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A61K 31/662 (2006.01) A61P 21/00 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2556802

The present invention relates to a method of increasing Adenosine Triphosphate levels in a mammal wherein 2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid ihhibits the leakage of the Adenosine Triphosphate-dependant enzyme Creatine Kinase. Via the inhibition of Creatine Kinase leakage, Adenosine Triphosphate is not utilized in the conversion of creatine to phosphocreatine, thereby making it available for use in muscular contractions. The increase in availability leads to longer endurance and more forceful muscular contractions.

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