C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/18 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 47/42 (2006.01) A61K 49/00 (2006.01) C07K 7/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2107556
Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood/brain barrier to molecules such as therapeutic agents or diagnostic agents. The permeabilizer A-7 or conformational analogues can be intravenously coad- ministered to a host together with molecules whose desired destination is the interstitial fluid compartment of the brain. Alterna- tively, the permeabilizer A-7 or conformational analogues can be administered sequentially with the molecule(s) of interest and these molecules can also be administered by routes other than intravascular. The permeabilizer A-7 or conformational analogues allow these molecules to penetrate the blood-brain barrier and arrive in the interstitial fluid.
Kozarich John W.
Malfroy-Camine Bernard
Musso Gary F.
Alkermes Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Increasing blood-brain barrier permeability with... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Increasing blood-brain barrier permeability with..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Increasing blood-brain barrier permeability with... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1531816