Indane derivatives

C - Chemistry – Metallurgy – 07 – C

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260/472.2, 260/2

C07C 63/337 (2006.01) C07C 17/32 (2006.01) C07C 33/34 (2006.01) C07C 33/50 (2006.01) C07C 45/46 (2006.01) C07C 49/792 (2006.01) C07C 69/76 (2006.01) C07D 295/088 (2006.01) C07D 295/14 (2006.01) C07D 295/194 (2006.01)

Patent

CA 1063618

A B S T R A C T The present invention relates to processes for preparing indane derivatives of general formula Image (I) in which: X represents a hydrogen or halogen atom; R1 and R2, which may be identical or different, each represents a hydrogen atom, an alkyl group containing 3 to 5 carbon atoms or a cycloalkyl group containing 3 to 7 carbon atoms; R3 represents a hydrogen atom or an alkyl group containing 1 to 5 carbon atoms; and Y represents -CH2OH or a group of formula -COOR4 in which R4 represents a hydrogen atom, 1/v(M) where M is a metal of valency v, or a group of formula -(CH2)n-NR5R6 wherein n is an integer of 1 to 5 and -NR5R6 is selected from the group consisting of di-(lower alkyl) amino, morpholino- lower alkyl, pyrrolidino-lower alkyl and piperidino-lower alkyl, and their pharmaceutically acceptable addition salts. The compounds of formula (I) and their salts are useful for the treatment of inflammations, algias, rheumatisms or pain syn- dromes in animals.

219396

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