Indane derivatives as mch receptor antagonists

Details Indane derivatives as mch receptor antagonists Indane derivatives as mch receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/4184 (2006.01)

Patent

CA 2623722

Provided herein are compounds of the formula (I): wherein A, R1, R2, R4, Ra and Rb are as those disclosed in the specification, as well as pharmaceutically acceptable salts thereof. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of obesity, hyperphagia, anxiety, depression and related disorders and diseases.

L'invention concerne des composés de formule (I) dans laquelle A, R1, R2, R4, Ra et Rb sont tels que définis dans la description, ainsi que des sels acceptables sur le plan pharmaceutique de ceux-ci. Ces composés et les compositions pharmaceutiques renfermant ceux-ci sont utiles dans le traitement de l'obésité, de l'hyperphagie, de l'anxiété, de la dépression et de troubles et maladies relatifs.

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