Indane derivatives as modulators of ion channels

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/52 (2006.01) A61K 31/54 (2006.01) A61P 29/00 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2611731

The present invention relates to indane derivatives of formula (I), in which the variables are as defined in the claims, useful as inhibitors of voltage- gated sodium and calcium ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Les dérivés d'indane de formule (I), dans laquelle des variables sont telles que définies aux revendications et servent d'inhibiteur des canaux sodiques voltage-dépendant et calciques ioniques. Des compositions pharmaceutiquement acceptables comprennent les composés de cette invention et les procédés d'utilisation des compositions dans le traitement de différents troubles.

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