Indane sulfonamide antiarrythmic agents

Details Indane sulfonamide antiarrythmic agents Indane sulfonamide antiarrythmic agents

C - Chemistry, Metallurgy

07

C

167/267, 167/276

C07C 211/60 (2006.01) A61K 31/18 (2006.01) C07C 311/08 (2006.01) C07D 211/28 (2006.01) C07D 265/30 (2006.01)

Patent

CA 1291164

Abstract Indane Sulfonamide Title: Antiarrhythmic Agents Compounds of the formula:- Image --- (A) and their salts, wherein each R, which is the same, is -NHSO2(C1-C4 alkyl),-NH2 or -NO2; X is 0 or a direct link; R1 is H, C1-C4 alkyl, C1-C4 alkoxy or halo; and n is 1 or 2, with the proviso that when X ix 0, n is 2. The compounds of the formula (A) in which each R is -NHSO2 (C1-C4 alkyl) are antiarrhythmic agents. The compounds in which R is -NH2 or -NO2 are synthetic intermediates.

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