Indanylamines and their use for local anesthesia and chronic...

A - Human Necessities – 61 – K

Patent

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A61K 31/535 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2622418

Dermal and mucosal formulations of 2-[2-(N-phenyl-N-2-indanyl) aminoethyl] piperidine, characterized by rapid dermal and mucosal absorption and long duration of therapeutic activity are provided. Also provided are solutions of 2-[2-(N-phenyl-N-2-indanyl) aminoethyl] piperidine for injection, characterized by short onset time and long duration of activity. Formulations containing both 2-[2-(N-phenyl-N-2-indanyl) aminoethyl] piperidine and capsaicin are also provided.

L'invention porte sur des formulations s'appliquant sur le derme et les muqueuses de 2-[2-(N-pheényl-N-2-indanyl) aminoéthyl] pipéridine, ces formulations étant caractérisées par leur absorption rapide par le derme et les muqueuses et par leur action thérapeutique de longue durée. L'invention porte également sur des solutions de 2-[2-(N-phényl-N-2-indanyl) aminoéthyl] pipéridine pour les injections, ces solutions étant caractérisées par un délai de réaction bref est une activité de longue durée. L'invention porte également sur des formulations contenant à la fois 2-[2-(N-phényl-N-2-indanyl) aminoéthyl] pipéridine et la capsaïcine.

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