Indazole compounds and methods for inhibition of cdc7

Details Indazole compounds and methods for inhibition of cdc7 Indazole compounds and methods for inhibition of cdc7

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/416 (2006.01) A61K 31/4162 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2648809

New compounds capable of acting as CDC7 inhibitors are provided. The compounds are useful either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of CDC7 mediated diseases, such as cancer. The compounds have the Formula (I) or (II), where the values of the variables are defined herein (I), (II).

La présente invention concerne de nouveaux composés susceptibles d'agir en tant qu'inhibiteurs de CDC7. Les composés peuvent être employés soit seuls, soit en combinaison avec au moins un agent thérapeutique supplémentaire, dans le traitement prophylactique ou thérapeutique de maladies faisant intervenir CDC7 telles que le cancer. Les composés sont de Formule (I) ou (II), les valeurs des variables étant définies dans la présente invention (I), (II).

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