Indazole derivatives and pharmaceutical compositions...

Details Indazole derivatives and pharmaceutical compositions... Indazole derivatives and pharmaceutical compositions...

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2557268

Compounds of Formula (I), or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein m, k, B, R1, R2 and R3 are those defined herein, and compositions comprising the same. Also provided are methods for preparing compounds of formula (I) and using the same in treating p38 mediated disorders in a patient.

L'invention concerne des composés représentés par la formule (I), dans laquelle m, k, B, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif, ou des sels, des solvates ou des promédicaments pharmaceutiquement acceptables de ces composés, ainsi que des compositions renfermant ceux-ci. L'invention concerne aussi des procédés d'élaboration des composés représentés par la formule (I), et des procédés d'utilisation de ceux-ci pour traiter, chez un patient, des troubles induits par p38.

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