Indazole derivatives that inhibit trpv1 receptor

Details Indazole derivatives that inhibit trpv1 receptor Indazole derivatives that inhibit trpv1 receptor

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 13/00 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2626593

Compounds of formula (I), wherein A, R1, R2, and R3 are defined in the specification, and which are useful as therapeutic compounds particularly for treating disorders or conditions associated with inflammation, pain, bladder overactivity, urinary incontinence, and other disorders caused by or exacerbated by TRPV1.

La présente invention concerne des composés de formule (I), où A, R1, R2, et R3 sont définis dans la description. Ces composés sont utiles en tant que composés thérapeutiques, en particulier pour le traitement de troubles ou de pathologies associés à l~inflammation, à une douleur, à une hyperactivité vésicale, à une incontinence urinaire, et à d~autres troubles induits ou exacerbés par TRPV1.

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