Indazoles having an action similar to that of a thyroid...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2422353

The invention relates to novel indazole derivatives of formula (I), in which Z represents O, S, CH2, CHF or CF2, and wherein R1-R7 have meanings as cited in Claim No. 1. The inventive indazole derivatives have an action similar to that of a thyroid hormone. The invention also relates to a method for producing said indazole derivatives, and to their use in medicaments.

L'invention concerne de nouveaux dérivés de l'indazole, de formule (I), dans laquelle, Z désigne O, S, CH¿2?, CHF ou CF¿2?, et où R?1¿-R?7¿ ont les significations spécifiées dans la revendication 1, ces dérivés ayant une action analogue à l'hormone thyroïdienne. L'invention concerne en outre leur procédé de fabrication et leur utilisation dans des médicaments.

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