C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2408448
The present invention relates to an indazole derivative, pharmaceutically acceptable salt, solvated product and isomer thereof substituted with 1,1- dioxoisothiazolidine which are useful as inhibitors for Cyclin Dependent Kinase(CDK). The present invention also relates to an agent for inhibiting and treating diseases involving cell proliferation, e.g., cancer, inflammation, restenosis, angiogenesis, etc. which comprises the indazole derivative as an active ingredient together with a pharmaceutically acceptable carrier.
La présente invention concerne un dérivé d'indazole ainsi qu'un sel pharmaceutiquement acceptable, un produit solvaté et un isomère dudit composé substitués avec de la 1,1-dioxoisothiazolidine et utiles comme inhibiteurs de la kinase dépendante des cyclines (CDK). La présente invention concerne également un agent destiné à inhiber et traiter des maladies impliquant une prolifération cellulaire, telles que le cancer, l'inflammation, la resténose, l'angiogenèse, etc. Cet agent renferme ce dérivé d'indazole en tant qu'ingrédient actif, ainsi qu'un excipient pharmaceutiquement acceptable.
Choi Sei Hyun
Chung Hyun Ho
Hong Chang Yong
Hwang Kwang Yeon
Jeong Shin Wu
Lg Life Sciences Ltd.
Robic
LandOfFree
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