Indene compounds

Details Indene compounds Indene compounds

C - Chemistry, Metallurgy

07

D

260/353.3, 260/2

C07D 317/70 (2006.01) C07D 295/096 (2006.01) C07D 405/10 (2006.01) C07D 407/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1269977

ABSTRACT OF THE DISCLOSURE The invention provides an indene compound represented by the following general formula (I): Image (I) wherein R1 means a lower alkyl group, R2 and R3 denote a lower alkyl group individually or an alkylenedioxy group in combination, and R4 and R5 mean individually a substituted or unsubstituted lower alkyl or aryl group or in combination a substituted or unsubstituted piperidino, piperazinyl or homopiperazinyl group together with the adjacent nitrogen atom, with a proviso that not both R4 and R5 are a methyl group at the same time. The compounds of this invention have the ability to increase coronary blood flow and thus are useful as therapeutic agents for angina pectoris.

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