Indenoindole compounds

Details Indenoindole compounds Indenoindole compounds

C - Chemistry, Metallurgy

07

D

C07D 209/94 (2006.01) A61K 31/40 (2006.01) C07D 209/70 (2006.01)

Patent

CA 2062830

2062830 9015800 PCTABS00003 Compounds of formulae (IA) and (IB), wherein R is hydrogen or a lower alkyl group, R1 and R2 are independently selected from hydrogen or a lower alkyl group, R3, R4 and R6 are independently selected from hydrogen, halogen or a lower alkyl group, R5 is hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH2 or NR11 COR12, R7, R8, R9 and R10 are independently selected from hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH2 or NR11 COR12, R11 is a hydrogen or a lower alkyl group, R12 is a lower alkyl group, with the proviso that when R is hydrogen then at least one of the substituents R1 to R10 is not hydrogen, or a salt thereof, are useful as antioxidants, within the medical and non-medical field, and that when R is hydrogen, methyl or neopentyl in formula (IA), then at least one of R1 to R10 is not hydrogen. Many of the compounds of formulae (IA) and (IB) are new and various methods for preparing them are described.

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