Indenoindole compounds ii

Details Indenoindole compounds ii Indenoindole compounds ii

C - Chemistry, Metallurgy

07

D

C07D 209/94 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2060897

2060897 9015799 PCTABS00003 Compounds of formulae (IA) or (IB) wherein R is hydrogen or a lower alkyl group or COR15, R1, R2, R11 and R12, are hydrogen or a lower alkyl group, R3, R4, R5 and R6 are hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group or a mono- or di-lower alkyl amino group, NH2 or NR13COR14, R7, R8, R9 and R10 are hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkyl-amino group, or NH13COR14 wherein R13, R14 and R15 are hydrogen or a lower alkyl group, enantiomers and salts thereof, with the proviso that when R is COR15 then at least one of R3 to R10 are hydroxy or a mono or di-lower alkylamino group, are useful as antioxidants, within the medical and non-medical field. Many of the compounds of formulae (IA) and (IB) are new and various methods for preparing them are described.

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