Indium photosensitizers for pdt

Details Indium photosensitizers for pdt Indium photosensitizers for pdt

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/409 (2006.01) A61K 31/555 (2006.01) A61K 41/00 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2336306

The invention disclosed herein involves a phototherapeutic pyrrolic core complexed with a non-radioactive Indium atom. Complexation of Indium by the pyrrolic core forms a metalopyrrolic compound which influences enables these compounds to localize at target sites a phototherapy. Such functionally aids in both detection and phototherapy of disease sites, or provides functionality that binds to site specific receptors of a target area such that the therapy is improved.

L'invention concerne un noyau pyrrolique photothérapeutique complexé avec un atome d'Indium non radioactif. La complexation d'indium au moyen du noyau pyrrolique permet la formation d'un composé métallopyrrolique qui agit sur la capacité de ces composés à se localiser au niveau de sites cibles de phytothérapie. Ladite fonctionnalité constitue une aide dans la détection et la photothérapie de sites pathologiques ou permet la liaison de ladite fonctionnalité aux récepteurs spécifiques au site d'une zone cible de sorte que la thérapie soit améliorée.

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