A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2274959
Individually dosed active substance-containing and, in particular, aromatic-containing, film-shaped administration form, rapidly disintegrating upon contact with a liquid, wherein the aromatic is present as an internal, liposoluble phase in the form of liquid droplets distributed within an outer, solid but water-soluble phase, is characterized in that the said outer phase contains: - at least 40% (w/w) polyvinyl alcohol - 0 to 30% (w/w) of a surface-active substance, and that the constituent amount of the inner phase, relative to the outer phase, is between 0.1 and 30% (w/w), in each case relative to the water-free portions.
L'invention concerne une forme galénique à dosage individuel, sous forme pelliculaire, contenant un principe actif et notamment une substance aromatique, se désagrégeant rapidement au contact de liquide. La substance aromatique est présente en tant que phase liposoluble intérieure répartie sous forme de gouttelettes liquides dans une phase extérieure solide mais soluble dans l'eau. Cette forme galénique se caractérise en ce que la phase extérieure contient: au moins 40 % (g/g) d'alcool de polyvinyle, entre 0 et 30 % (g/g) d'une substance tensioactive. La proportion quantitative de la phase intérieure, par rapport à la phase extérieure, se situe entre 0,1 et 30 % (g/g), rapportée dans chacun des cas à des fractions anhydres.
Horstmann Michael
Laux Wolfgang
Blake Cassels & Graydon Llp
Lts Lohmann Therapie-Systeme Ag
Lts Lohmann Therapie-Systeme Gmbh
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