Indole-3-carbonyl and indole-3-sulfonyl derivatives as...

Details Indole-3-carbonyl and indole-3-sulfonyl derivatives as... Indole-3-carbonyl and indole-3-sulfonyl derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2218020

The present invention provides compounds of formula (I) and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.

La présente invention décrit des composés de formule (I) et leurs sels pharmaceutiquement acceptables qui sont des antagonistes puissants du facteur d'activation des plaquettes (PAF) et qui sont utilisés dans le traitement de troubles relatifs au PAF, tels que l'asthme, l'état de choc, le syndrome de détresse respiratoire, l'inflammation aiguë, le rejet d'organes transplantés, l'ulcération gastro-intestinale, les maladies allergiques de la peau, l'immunité retardée des cellules, la parturition, la maturation pulmonaire du foetus et la différenciation cellulaire.

Affiliated with

Also associated with

Rating

Indole-3-carbonyl and indole-3-sulfonyl derivatives as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole-3-carbonyl and indole-3-sulfonyl derivatives as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole-3-carbonyl and indole-3-sulfonyl derivatives as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1506076