C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/04 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2581338
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
L'invention porte sur des composés de l'acide indole acétique jouant le rôle d'antagonistes du récepteur CRTH2, et sur l'utilisation de ces composés: pour inhiber la fixation de la prostaglandine D2 et de ses métabolites, ou de certains métabolites du type thromboxane, au récepteur CRTH2, et pour traiter des troubles par cette inhibition.
Bennani Youssef L.
Gleason Elizabeth Ann
Robarge Michael Joseph
Tumey L. Nathan
Athersys Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Wyeth
LandOfFree
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