Indole and indoline derivatives

Details Indole and indoline derivatives Indole and indoline derivatives

C - Chemistry, Metallurgy

07

D

260/319, 260/320

C07D 209/08 (2006.01) C07C 205/57 (2006.01) C07D 209/12 (2006.01) C07D 209/30 (2006.01) C07F 9/54 (2006.01)

Patent

CA 1149811

A B S T R A C T "INDOLE AND INDOLINE DERIVATIVES" Indole and indoline derivatives of the formula:- Image wherein indicates a double bond or a single bond between carbon atoms. R1 represents an alkyl group containing 1 to 6 carbon atoms (which may be substituted by one or more than one of the same type of substituents selected from the hydroxy group, alkenyl groups containing 2 to 5 carbon atoms, and alkanoyloxy groups containing 2 to 7 carbon atoms) or a hydrogen atom, and one of the symbols R2 represents an alkyl group containing 6 to 24 carbon atoms and the other symbol R2 represents an alkyl group containing 1 to 24 carbon atoms. or a hydrogen atom, and R3 represents an alkyl group containing 1 to 6 carbon atoms or a hydrogen atom, are new compounds possessing useful pharmacological properties. They are of use in the treatment of diabetes mellitus, hyperlipoproteinaemic states, of atherosclerosis, and of associated disorders. Pharmaceutical compositions containing the compounds are described and so are numerous processes for preparing the compounds.

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