Indole and indoline derivatives and methods of use thereof

Details Indole and indoline derivatives and methods of use thereof Indole and indoline derivatives and methods of use thereof

C - Chemistry, Metallurgy

07

D

C07D 487/18 (2006.01) A61K 31/33 (2006.01) A61P 25/00 (2006.01) C07D 471/08 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2737031

The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein in a, R1-, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.

La présente invention concerne des dérivés dindole et dindoline de formule (I), (II), (III), (IV), (V), ou (VI) où a, R1, R2, R3, R4, R5, U, V, W, X, Y, et Z sont comme définis dans la spécification. La présente invention concerne en outre des compositions comprenant de tels composés, et des procédés de traitement daffections pathologiques utilisant de tels composés et compositions, et des procédés pour identifier de tels composés.

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