C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/08 (2006.01) A61K 31/445 (2006.01) C07D 401/06 (2006.01) C07D 403/12 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2487542
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with new piperidine 4-alkenyl derivatives that possess unique antiviral activity. More particularly, the present invention relates to compounds useful for the treatment of HIV and AIDS. The compounds of the invention for the general Formula I: (I) wherein: Z is ; Q is selected from the group consisting of: ; -W-is .
L'invention concerne des compos~s poss~dant des propri~t~s th~rapeutiques et bioactives, ainsi que leurs compositions pharmaceutiques et leur m~thode d'utilisation. L'invention concerne en particulier de nouveaux d~riv~s de 4-alc~nyl-pip~ridine poss~dant une activit~ antivirale unique. L'invention concerne plus particulirement des compos~s utiles pour traiter le VIH et le SIDA. Les compos~s selon l'invention sont repr~sent~s par la formule g~n~rale (I), Z repr~sentant (II), Q ~tant choisi dans le groupe comprenant (III), (IV), (V), (VI) et (VII) et -W- repr~sentant (VIII).
Bachand Carol
Deon Daniel H.
James Clint A.
Kadow John F.
Meanwell Nicholas A.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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