C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/496 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 209/20 (2006.01) C07D 209/42 (2006.01) C07D 231/56 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 333/24 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2445190
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with amido piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
L'invention concerne des composés présentant des propriétés médicamenteuses et bioactives, leurs compositions pharmaceutiques, ainsi que leur méthode d'utilisation. Plus particulièrement, cette invention concerne des dérivés d'amidopipérazine. Ces composés présentent une activité antivirale unique, qu'ils soient utilisés de manière isolée ou en combinaison avec d'autres agents antiviraux, anti-infectieux, immunomodulateurs ou inhibiteurs de l'entrée du VIH. Plus particulièrement, la présente invention se rapporte au traitement du VIH et du sida.
Bender John A.
Kadow John F.
Meanwell Nicholas A.
Wallace Owen B.
Wang Tao
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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