Indole carbamates as leukotriene antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 401/06 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 231/56 (2006.01) C07D 405/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2080405

171/GL63 18486 TITLE OF THE INVENTION INDOLE CARBAMATES AS LEUKOTRIENE ANTAGONISTS ABSTRACT OF THE DISCLOSURE Compounds having the formula I: Image are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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